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A Comparative Study of the Redox-Cycling of a Quinone (Rifamycin S) and A Quinonimine (Rifabutin) Antibiotic by Rat Liver Microsomes

โœ Scribed by D.N.Ramakrishna Rao; Arthur I. Cederbaum


Book ID
114276433
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
337 KB
Volume
22
Category
Article
ISSN
0891-5849

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Spontaneous S6 phosphatase activities dephosphorylating Ser(P)-235 and Ser(P)-236 of the ribosomal protein S6 were measured and compared in microsomes and cytosol of rat liver. The substrate used, small (40S) ribosomal subunits 32P-labelled in vitro by protein kinase A, contained phosphorylated S6 (