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A comparative study of histone deacetylases of plant, fungal and vertebrate cells

✍ Scribed by Thomas Lechner; Alexandra Lusser; Gerald Brosch; Anton Eberharter; Maria Goralik-Schramel; Peter Loidl

Book ID
113269862
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
771 KB
Volume
1296
Category
Article
ISSN
0167-4838

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## Abstract In cells with an altered __p53__ gene, the expression of p21^__WAF1__/__CIP1__^, a potent inhibitor of cyclin‐dependent kinases, can be induced by histone deacetylase (HDAC) inhibitors via a __p53__‐independent pathway, which may play a critical role in arrest of cell growth. Accordingl