A comparative study of glucose meter accuracy during biochemical hypoglycaemia in humans

✍ Scribed by Thomson, GA ;Galloway, P ;Murdoch, J ;Fisher, BM ;Semple, CG

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 418 KB
• Volume: 15
• Category: Article
• ISSN: 1357-8170
• DOI: 10.1002/pdi.1960150504

✦ Synopsis

Abstract

Four glucose meters (Medi Sense Pen 2, Boehringer Mannheim Reflolux‐S and Mini‐Accutrend, and Lifescan One Touch II) were compared with laboratory glucose estimation during hypoglycaemia in human subjects. During hypoglycaemia the bias was −0.15 ± 0.6mmol/L (bias ±95% confidence interval) for the Medi Sense Pen 2, +0.2 ±0.6 mmol/L for the Reflolux‐S, −0.4 ±1.6 mmol/L for the Mini‐Accutrend, and −0.1 ±1.0 mmol/L for the One Touch II, giving limits of agreement of −0.75 to +0.45 mmol/L, −0.4 to +0.8 mmol/L, −2.0 to +1.2 mmol/L and‐1.1 to +0.9 respectively. The precision of the reference method was ±0.1 mmol/L in the hypoglycaemic range. We conclude that none of the meters assessed were as accurate as laboratory glucose estimation but that the Medi Sense Pen 2 and Reflolux‐S may be useful in clinical practice to confirm the presence of biochemical hypoglycaemia.