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A comparative pharmacokinetic study of valpromide and valproic acid after intravenous administration in humans

โœ Scribed by BIALER, M; RUBINSTEIN, A; DUBROVSKY, J; RAZ, I; ABRAMSKY, O


Book ID
121967281
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
648 KB
Volume
23
Category
Article
ISSN
0378-5173

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The dose-dependent pharmacokinetics of caeic acid (CA) were studied in rabbits. Three dierent doses (5, 10, and 25 mg kg 71 ) were administered intravenously to six rabbits each. The concentrationยฑtime proยฎles for CA could be ยฎtted by a twocompartment model for each dose. The results showed that tot