A comparative evaluation of continuous flow fast atom bombardment and ion spray ionization techniques for the simultaneous determination of alkyltrimethylammonium surfactants by mass spectrometry
✍ Scribed by Silvia A. Coran; Massimo Bambagiotti-Alberti; Valerio Giannellini; Gloriano Moneti; Giuseppe Pieraccini; Andrea Raffaelli
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 81 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-4198
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✦ Synopsis
This study compares the performances of two mass spectrometric ionization techniques, i.e. fast atom bombardment (FAB) and ion spray ionization (ISI), in the simultaneous quantitation of dodecyl-, tetradecyl-and hexadecyltrimethylammonium halides in aqueous media. Continuous flow FAB and flow injection analysis (FIA)-ISI, both in selected ion monitoring and selected reaction monitoring modes, were evaluated. Quantitation was performed by dilution with deuterium labelled homologues synthesized by a simple procedure. A comparison of the data indicated FIA-ISI as the more sensitive (limit of detection = 10 ppb). Good linearity, precision and accuracy were obtained by the tested techniques in the concentration range 0.125-4.0 ng mL À1 . Hair softeners, commercial surfactant mixtures and hematology lysing reagents were used as test samples.