A Common Variant in DRD3 Receptor Is Associated with Autism Spectrum Disorder
β Scribed by Mariken de Krom; Wouter G. Staal; Roel A. Ophoff; Judith Hendriks; Jan Buitelaar; Barbara Franke; Maretha V. de Jonge; Patrick Bolton; David Collier; Sarah Curran; Herman van Engeland; Jan M. van Ree
- Book ID
- 119198049
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 168 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0006-3223
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## Abstract Individuals with autism spectrum disorders (ASDs) have impairments in executive function and social cognition, with males generally being more severely affected in these areas than females. Because the dopamine D1 receptor (encoded by DRD1) is integral to the neural circuitry mediating