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A common genetic risk factor for colorectal and prostate cancer

✍ Scribed by Haiman, Christopher A; Le Marchand, Loïc; Yamamato, Jennifer; Stram, Daniel O; Sheng, Xin; Kolonel, Laurence N; Wu, Anna H; Reich, David; Henderson, Brian E

Book ID
109919614
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
140 KB
Volume
39
Category
Article
ISSN
1061-4036

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BACKGROUND. Genetic polymorphisms and expression of steroid receptors may explain why some individuals are more at risk of developing prostate cancer. Some risk factors often discussed are androgen stimulation, and vitamin A and D deficiency. Long CAG-repeats in exon 1 of the androgen receptor (AR)