A common and stereoselective strategy for the synthesis of N,O,O,O-tetra-acetyl d-ribo-(2S,3S,4R)-phytosphingosine and 2-epi-jaspine B
โ Scribed by G. Srinivas Rao; B. Venkateswara Rao
- Book ID
- 113929732
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 429 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
## Treatment of methyl 5-deoxy-S-C-(diethoxyphosphinyl)-2.3-O-isopropylidene-p-D-ribofuranoside with sodium dihydrobis(2-methoxyethoxy)aluminate, followed by hydrogen peroxide, mineral acid, and hydrogen peroxide, gave 5deoxy-5-C-(hydroxyphosphinyl)-a,P-D-ribopyranoses in 40-45% overall yield. The
Various sugar analogs possessing a phosphorus atom in the hemiacetal ring have been preparedIe because of the interest in their physicochemical properties and also the potential utility of'their biological activity. Compared with a large number of the analogs having an alkyl-or aryl-phosphinyl group