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A CoMFA study of histamine H3 receptor agonists

✍ Scribed by Jukka Gynther; Antti Poso; Jari Kova;ainen; Hans Christiaans; Leena Tuomisto


Book ID
117628751
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
136 KB
Volume
4
Category
Article
ISSN
0928-0987

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A step-wise CoMFA-based procedure was applied to a series of 51 C2-oxyadenosines in order to select the most predictive conformation for binding to A 2A adenosine receptor. The highest correlation and predictive power was found for conformers with the side chain at the 2position oriented in the dire