Model predicting the teratogenic potenti
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Ritchie, H. E.; Webster, W. S.; Eckhoff, C.; Oakes, D. J.
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Article
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1998
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John Wiley and Sons
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English
β 218 KB
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Retinyl palmitate (RP) is a known laboratory animal teratogen inducing abnormalities of the second visceral arch when administered on day 9 of gestation in the rat. However, there are significant problems when attempting to extrapolate this result to the human. A combined in vivo/in vitro model was