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A combined technological metabolomic strategy for the identification of metabolites in human urine

✍ Scribed by J.R. Sheedy; P.R. Ebeling; R.E.H. Wettenhall; P.R. Gooley; M. McConville


Book ID
116321459
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
426 KB
Volume
44
Category
Article
ISSN
8756-3282

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Urine samples taken from a person who ingested nortriptyline.HC1 (4 X 25 mg. daily) were extracted by a two-phase procedure with ether. A first screening by UV spectrophotometry showed the presence of compound(s) with basic character but different from free nortriptyline. The TLC separation of aliqu