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A combined micro-PET/CT scanner for small animal imaging

✍ Scribed by Meei-Ling Jan; Yu-Ching Ni; Kuo-Wei Chen; Hsing-Ching Liang; Keh-Shih Chuang; Ying-Kai Fu


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
442 KB
Volume
569
Category
Article
ISSN
0168-9002

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✦ Synopsis


A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET s R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET s R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging.


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