A combined, 6-exo-dig radical cyclization-palladium catalyzed allylic amination, approach to aminocarbasugar analogs: synthesis of novel N-substituted aminocyclitols from d-mannose

✍ Scribed by Ana M. Gómez; Eduardo Moreno; Serafı́n Valverde; J.Cristóbal López

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 143 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01919-6

✦ Synopsis

A novel approach, which features a stereoselective 6-exo-dig radical cyclization and a palladium-catalyzed allylic amination, permits a six steps synthesis of aminocyclitol analogs from D-mannose.