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A Combinatorial Scaffold Approach toward Kinase-Directed Heterocycle Libraries

✍ Scribed by Ding, Sheng; Gray, Nathanael S.; Wu, Xu; Ding, Qiang; Schultz, Peter G.


Book ID
111939112
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
83 KB
Volume
124
Category
Article
ISSN
0002-7863

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## Abstract The protein surface is the interface through which a protein molecule senses the external world. The composition of this interface, in charged, polar and/or hydrophobic residues is crucial for both the activity and stability of the protein. Protein immobilization on surfaces has been ex