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A collaborative case-control study of nutrient intake and pancreatic cancer within the search programme

✍ Scribed by G. R. Howe; P. Ghadirian; H. B. Bueno de Mesquita; W. A. Zatonski; P. A. Baghurst; A. B. Miller; A. Simard; J. Baillargeon; F. de Waard; K. Przewozniak; A. J. McMichael; M. Jain; C. C. Hsieh; P. Maisonneuve; P. Boyle; A. M. Walker

Publisher
John Wiley and Sons
Year
1992
Tongue
French
Weight
901 KB
Volume
51
Category
Article
ISSN
0020-7136

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✦ Synopsis

Case-control studies of pancreatic cancer were conducted in 5 populations with moderate to high rates and differing dietary practices, using a common protocol and questionnaire. Comprehensive diet histories were completed for a total of 802 cases and I669 controls identified in Adelaide (Australia), Montreal and Toronto (Canada), Utrecht (The Netherlands) and Opole (Poland). Positive associations were observed with intake of carbohydrates and cholesterol, and inverse associations with dietary fiber and vitamin C. These relationships were generally consistent among the 5 studies, and showed statistically significant and generally monotonic dose-response relationships. The relative risks for highest vs. lowest quintile of intake were estimated for carbohydrates to be 2.57 (95% confidence interval I .644.03), cholesterol 2.68 (I . 7 2 4 I7), dietary fiber 0.45

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