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A Cold-Passaged, Attenuated Strain of Human Respiratory Syncytial Virus Contains Mutations in the F and L Genes

โœ Scribed by Mark Connors; James E. Crowe Jr.; Cai-Yen Firestone; Brian R. Murphy; Peter L. Collins

Book ID
112270390
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
436 KB
Volume
208
Category
Article
ISSN
0042-6822

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โœ James E. Crowe; Cai-Yen Firestone; Stephen S. Whitehead; Peter L. Collins; Brian ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 381 KB

A cold-passaged (cp) temperature-sensitive (ts) mutant of human respiratory syncytial virus designated RSV cpts-248 was previously derived by random chemical mutagenesis of the non-ts mutant cp-RSV that possesses one or more host range mutations. We previously demonstrated in rodents and seronegativ