A CMR study of the biosynthesis of chloramphenicol
โ Scribed by Murray H.G. Munro; Masao Taniguchi; Kenneth L. Rinehart Jr.; David Gottlieb
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 209 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
The biosynthesis of the medically important antibiotic chloramphenicol (1, Figure ) has been a subject of considerable interest during the past 20 years. Early experiments2 suggested the operation of a shikimate pathway3 and this was supported by the low incorporation, with high
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An in oitro method for measuring the percutaneous absorption of chloramphenicol solutions is described. The apparatus consists essentially of thermostated upper and lower chambers fabricated from methyl methacrylate, with the membrane sandwiched between the chambers. The upper chamber holds the solu