A Closer Look at the Mean Residence Time (MRT) Concept Based on Statistical Moments

On the statistical moments transformatio

On the statistical moments transformation in pharmacokinetic models: A study of the rate parameter and the mean residence time estimates

✍ J.H. Matis; D.R. Olson; K.B. Gerald 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 690 KB

This paper simulates the sampling distributions of the rate parameter and the mean residence time (MRT) estimators for a specific two-compartment model. Two forms of measurement error, one additive and the other multiplicative, and two forms of weighting structures, one unweighted and the other wei