𝔖 Bobbio Scriptorium
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A clinical evaluation of a new method for HBV DNA quantitation in patients with chronic hepatitis B

✍ Scribed by Khakoo, S. I.; Soni, P. N.; Brown, D.; Dusheiko, G. M.

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
494 KB
Volume
50
Category
Article
ISSN
0146-6615

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✦ Synopsis

Selection of HBsAg-positive patients for antiviral therapy requires an estimation of disease activity and viral replication. Serum transaminases and histological analysis are commonly used t o as-

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## Abstract A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of doxofylline (DFL) with 300 Β΅L human serum using imipramine as the internal standard (IS). The API‐3000 LC‐MS/MS was operated under multiple reaction‐monitoring mode using the electrosp