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A clinical and pharmacological study of arsenic trioxide in advanced multiple myeloma patients

✍ Scribed by Rousselot, P; Larghero, J; Arnulf, B; Poupon, J; Royer, B; Tibi, A; Madelaine-Chambrin, I; Cimerman, P; Chevret, S; Hermine, O


Book ID
110055948
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
121 KB
Volume
18
Category
Article
ISSN
0887-6924

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Phase II clinical trial of arsenic triox
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In patients with multiple myeloma, there is preclinical justification to combine arsenic trioxide (ATO and As 2 O 3 ) with DVd (Doxil TM , vincristine, and dexamethasone) for newly diagnosed patients. Eleven patients on this phase II trial received 0.15 mg/kg of ATO for five consecutive days followe