Nonrandom chromosome changes in multiple
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D'Alessandro, Elvira ;Cola, Mario Di ;Lo Re, Maria Luisa ;Ligas, Claudio ;Vaccar
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Article
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1990
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John Wiley and Sons
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English
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In order to study the role of genetic factors in multiple sclerosis, cytogenetic analysis was performed on 48 patients with the clinically defined disease. We found a high incidence of subjects (50%) with abnormal chromosomes, showing premature centromere division of the X chromosome and structural