𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Chiral β,δ-Dioxo-ϵ-sulfinyl Ester in a Convergent Enantioselective Synthesis towards the C1–C13 Polyol Fragment of Amphotericin B

✍ Scribed by Guy Solladié; Nicole Wilb; Claude Bauder


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
343 KB
Volume
1999
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

✦ Synopsis


This paper describes an efficient stereocontrolled and reduction of a chiral β,γ-dioxo-ε-sulfinyl ester to obtain antior syn-1,3-diols. convergent approach towards the C 1 -C 13 polyol fragment of amphotericin B. The strategy is based on the stereoselective