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A chimeric opioid peptide with mixed μ agonist/δ antagonist properties

✍ Scribed by Weltrowska, G. ;Lemieux, C. ;Chung, N.N. ;Schiller, P.W.

Book ID
110893733
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
97 KB
Volume
63
Category
Article
ISSN
1397-002X

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The discovery of the prototype ␦ opioid antagonists TIPP (H-Tyr-Tic-Phe-Phe-OH) and TIP (H-Tyr-Tic-Phe-OH) in 1992 was followed by extensive structure-activity relationship studies, leading to the development of analogues that are of interest as pharmacological tools or as potential therapeutic agen