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A chimeric antigen receptor against prostate-specific membrane antigen, a tumor vasculature target

✍ Scribed by Stephen P Santoro,Soorin Kim,Dimitrios Alatzoglou…

Book ID
126381323
Publisher
Springer (Biomed Central Ltd.)
Year
2013
Tongue
English
Weight
73 KB
Volume
1
Category
Article
ISSN
2051-1426

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## Abstract Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein, which is overexpressed manifold on prostate cancer as well as neovasculature of most of the solid tumors, but not in the vasculature of the normal tissues. This unique expression of PSMA makes it an impo