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A chemiluminescent probe with a Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, specific and sensitive for O2− production in phagocytizing macrophages

✍ Scribed by Katsuaki Sugioka; Minoru Nakano; Satonori Kurashige; Yuki Akuzawa; Toshio Goto

Book ID
115917919
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
387 KB
Volume
197
Category
Article
ISSN
0014-5793

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Chemiluminescence probe with Cypridina l
Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2−
✍ Minoru Nakano; Katsuaki Sugioka; Yoshio Ushijima; Toshio Goto 📂 Article 📅 1986 🏛 Elsevier Science 🌐 English ⚖ 519 KB

The Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one (CLA), in Hanks' balanced salt solution, emitted a weak luminescence which was not affected by superoxide dismutase or catalase and was not augmented by resting human granulocytes. In contrast, activated granulo

Measurement of rate constants for quench
Measurement of rate constants for quenching singlet oxygen with aCypridina luciferin analog (2-methyl-6-[p-methoxyphenyl]-3,7-dihydroimidazo[1,2-a]pyrazin-3-one) and sodium azide
✍ Mashiko, Shinro ;Suzuki, Nobutaka ;Koga, Satoshi ;Nakano, Minoru ;Goto, Toshio ; 📂 Article 📅 1991 🏛 John Wiley and Sons ⚖ 347 KB 👁 1 views

## Abstract The rate constants for [^1^O~2~] [MCLA] and [^1^O~2~][NaN~3~] were measured by quenching the near‐infrared emission (^1^Δ~g~→^3^∑~__g__~) in steady state with MCLA and NaN~3~, respectively. ^1^O~2~ was constantly generated by energy transfer to O~2~ from Ar laser‐excited Rose Bengal. Th