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A Chemical Concept for the Treatment of Tay–Sachs Disease
✍ Scribed by Dr. Thomas Kolter
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 419 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0044-8249
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A screening program for the detection of Tay-Sachs disease (TSD) carriers in the ultra Orthodox community of Ashkenazi J e w s has operated in Israel since 1986. The purpose of this program is the prevention of marriages of 2 heterozygotes. The screened individuals are mostly couples in the engageme
Tay-Sachs disease (TSD), a neurodegenerative disorder resulting from a deficiency of the lysosomal enzyme hexosaminidase A (HexA), clusters in Ashkenazic Jews. Population-based screening programs to detect carriers of TSD genes by means of HexA assays have been active since the 1970s. The recent cha