A characterization of γ-glutamyltranspeptidase in normal, perinatal, premalignant and malignant rat liver
✍ Scribed by Susan J. Sulakhe; W.Wayne Lautt
- Book ID
- 103121055
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 971 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0020-711X
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Earlier work describing increased biliary excretion of the acetaminophen-cysteine conjugate advanced the hypothesis that streptozotocin-induced diabetes increases c-glutamyltranspeptidase (GGT) expression in Sprague-Dawley rats. To test this hypothesis, rats were divided into control, diabetic, and
## Abstract An improved staining method for γ‐glutamyltranspeptidase (GGT) was developed using Vibratome‐prepared microslices. Microscopic precursor cell populations of preneoplastic foci positive for the marker enzyme were detectable sequentially in rat liver by tracing back from 5 to 1 week after