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A characterisation of long-term depression induced by metabotropic glutamate receptor activation in the rat hippocampus in vitro

✍ Scribed by Stephen M. Fitzjohn; Mary J. Palmer; Jolyon E. R. May; Anne Neeson; Stephen A. C. Morris; Graham L. Collingridge


Book ID
111119522
Publisher
Cambridge University Press
Year
2001
Tongue
English
Weight
425 KB
Volume
537
Category
Article
ISSN
0022-3751

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Using an in vitro slice preparation, we studied the effects, on parallel fiber (PF)-mediated EPSPs, of coactivation of metabotropic-glutamate receptors and of voltage-gated calcium (Ca) channels of Purkinje cells (PCs) by bath application of 50 microM trans-1-amino-cyclopentyl-1,3-dicarboxylate (tra