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A change in the pattern of activity affects the developmental regression of the purkinje cell polyinnervation by climbing fibers in the rat cerebellum

✍ Scribed by P.R Andjus; L Zhu; R Cesa; D Carulli; P Strata

Book ID
117491376
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
418 KB
Volume
121
Category
Article
ISSN
0306-4522

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## Abstract Climbing fiber (CF)–‐Purkinje cell (PC) relationships were studied electrophysiologically on the cerebellum of 8 to 15 day old rats. Some animals were rendered agranular by x‐irradiation from birth; some others were treated with 3‐acetyl pyridine 3 days before study to selectively destr

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## Abstract Myosin Va is an actin‐based molecular motor that is involved in organelle transport and membrane trafficking. Here, we explored the role of myosin Va in the formation of synaptic circuitry by examining climbing fiber (CF) innervation of Purkinje cells (PCs) in the cerebella of __dilute‐