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A change in nucleotide selectivity pattern of porphyrin derivatives after immobilization on gold nanoparticles

✍ Scribed by Pavel Rezanka; Kamil Záruba; Vladimír Král


Book ID
104095778
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
495 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis


Two porphyrin-quaternized brucine salts 1 and 2 were immobilized on 3-mercaptopropanoic acid derivatized gold nanoparticles. The porphyrin modified nanoparticles were purified and characterized by a variety of techniques including electron microscopy and absorption spectroscopy in the UV-vis range. Interactions of nucleotides with 1 and 2 in solution and after immobilization of 1 and 2 on the surface of the nanoparticles were studied. A change in the selectivity pattern towards nucleotides as an effect of the porphyrin derivative immobilization is demonstrated.