A central inhibitory action of 5-hydroxytryptamine in the leech
β Scribed by Sawada, Masashi ;Coggeshall, Richard E.
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 391 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0022-3034
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## Abstract 5βHydroxytryptamine (5βHT), a neurotransmitter and neuromodulator in the central nervous system of the leech __Hirudo medicinalis__ hyperpolarizes the giant glial cell in the neuropil of segmental ganglia at micromolar concentrations. The 5βHTβevoked glial response (EC~50~ β2.5 ΞΌM) is m
Several days after the completion of the early phase of cell proliferation that generates most of the leech central nervous system, the pair of "sex ganglia" in the two reproductive segments of the midbody undergo a second period of neurogenesis that gives rise to several hundred peripherally induce