A census of human cancer genes
โ
Futreal, P. Andrew; Coin, Lachlan; Marshall, Mhairi; Down, Thomas; Hubbard, Timo
๐
Article
๐
2004
๐
Nature Publishing Group
๐
English
โ 175 KB
Numerous alterations in DNA sequence underlie the development of every neoplasm. These sequence variants can be transmitted through the germline and result in susceptibility to cancer, or can arise by somatic mutation. A central aim of cancer research has been to identify the mutated genes that are