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A Cell Protection Screen Reveals Potent Inhibitors of Multiple Stages of the Hepatitis C Virus Life Cycle

โœ Scribed by Karuppiah Chockalingam; Rudo Simeon; Charles Rice; Zhilei Chen


Book ID
113458260
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
68 KB
Volume
86
Category
Article
ISSN
0166-3542

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We developed an in vitro system that can be used for the study of the life cycle of a wide variety of blood-borne hepatitis C viruses (HCV) from various patients using a three-dimensional hollow fiber culture system and an immortalized primary human hepatocyte (HuS-E/2) cell line. Unlike the convent