A Colorimetric Assay for High-Throughput
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Joel C. Bronstein; Peter C. Weber
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Article
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2001
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Elsevier Science
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English
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Herpes simplex virus type 1 (HSV-1) encodes a deoxyribonuclease that is frequently referred to as alkaline nuclease (AN) because of its elevated pH optimum. Studies with recombinant viruses which contain deletions in the HSV-1 gene encoding AN have indicated that this enzyme is required for efficien