Does elimination of placebo responders i
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Sandra Lee; John R. Walker; Laura Jakul; Kathryn Sexton
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Article
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2004
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John Wiley and Sons
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English
β 109 KB
The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the tr