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A case report of hereditary leiomyomatosis and renal cell cancer

✍ Scribed by Melissa K. Frey; Michael J. Worley Jr; Katherine P. Heyman; Thomas A. Caputo

Book ID: 113436481
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 387 KB
Volume: 202
Category: Article
ISSN: 1097-6868
DOI: 10.1016/j.ajog.2010.03.042

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## Abstract Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a tumor predisposition syndrome with cutaneous and uterine leiomyomatosis as well as renal cell cancer (RCC) as its clinical manifestations. HLRCC is caused by heterozygous germline mutations in the __fumarate hydratase (fumaras