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A case-only study of interactions between metabolic enzyme polymorphisms and industrial pollution in childhood acute leukemia

✍ Scribed by You Yang; Ying Tian; Xingming Jin; Chonghuai Yan; Fan Jiang; Yiwen Zhang; Jingyan Tang; Xiaoming Shen


Book ID
116454810
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
191 KB
Volume
28
Category
Article
ISSN
1382-6689

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## Abstract The metabolism of xenobiotics is complex and involves multiple steps and multiple enzymes. Genetic variation in the genes encoding these enzymes as well as the level of exposure to the substrates of these enzymes could alter metabolism and clearance of potential carcinogens and thus alt