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A case of type 2 GM1-gangliosidosis with long survival

โœ Scribed by Kikuchi, Koichi; Minami, Ryoji; Kudoh, Toru; Nakao, Toru; Tsugawa, Satoshi


Book ID
123019004
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
321 KB
Volume
4
Category
Article
ISSN
0387-7604

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Uptake of radioactivity from 14C-galactose into gangliosides by cultured skin fibroblasts was studied. GM3 was the major ganglioside in control human fibroblasts. An increase of GM1 was demonstrated in GM1-gangliosidosis fibroblasts. The degree of GM1 accumulation was correlated with the clinical ty