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A Case of Sjögren's Syndrome With Repeatedly Negative Findings on Lip Biopsy

✍ Scribed by James Katz; Harold Yamase; Ann Parke

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
833 KB
Volume
34
Category
Article
ISSN
0004-3591

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✦ Synopsis

We report a case of Sjögren's syndrome characterized by keratoconjunctivitis sicca, parotid swelling, reduced salivary flow, and abnormalities on nuclear scanning. Two labial gland biopsies showed complete atrophy. Biopsy of an enlarged submandibular gland revealed lymphoid follicles and glandular replacement consistent with the diagnosis of Sjögren's syndrome. This case supports the concept that a negative finding on labial biopsy does not rule out a diagnosis of Sjögren's syndrome.

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