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A case of primary hyperparathyroidism with severe bone and renal changes

✍ Scribed by Rika Jimbo-Saito; Yoshifumi Ubara; Hiraku Kadoguchi; Tatsuya Suwabe; Shohei Nakanishi; Yasushi Higa; Junichi Hoshino; Naoki Sawa; Hideyuki Katori; Fumi Takemoto; Hiroaki Nishimura; Michio Nakamura; Shinji Tomikawa; Kenichi Ohashi; Kennmei Takaichi

Publisher
Springer
Year
2009
Tongue
English
Weight
408 KB
Volume
27
Category
Article
ISSN
0914-8779

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## Abstract Differences in bone mineral density (BMD) patterns have been recently reported between multiple endocrine neoplasia type 1–related primary hyperparathyroidism (HPT/MEN1) and sporadic primary HPT. However, studies on the early and later outcomes of bone/renal complications in HPT/MEN1 ar

Role of citric acid in primary hyperpara
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Nephrolithiasis is presented in 18-40% of patients with primary hyperparathyroidism. Our work suggests that citrate, an inhibitor of calcium salts, could be involved in the presence of renal lithiasis because hyperparathyroid stone formers show less citrate elimination than nonstone formers.