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A case of multiple myeloma IgG(λ)type with low molecular weight κ light chain

✍ Scribed by Mayumi Imoto; Kinji Ishikawa; Kazuhiko Yamamoto; Hyogo Sinohara; Ikunosuke Sakurabayashi; Kinji Matsuura; Atsuko Koyama; Atushi Horiuchi; Toshiyuki Akiyama; Yasuhiro Ohba; Itaru Furuta

Book ID
117075879
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
409 KB
Volume
277
Category
Article
ISSN
0009-8981

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✍ Taisiya A. Parkhomenko; Galina A. Legostaeva; Boris M. Doronin; Valentina N. Bun 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB

## Abstract We present the first evidence demonstrating that small fractions of IgGs of all four subclasses (IgG1–IgG4) are catalytically active in the hydrolysis of DNA and on average their relative activity (nM supercoiled DNA/1mg IgG/1 h) increases in the order: IgG1 (0.58) < IgG2 (0.94) < IgG3