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A case of hepatocellular carcinoma with multiple lung, spleen, and remnant liver metastasis successfully treated by combination chemotherapy with the novel oral DPD-inhibiting chemotherapeutic drug S-1 and interferon-α

✍ Scribed by Masato Nakamura; Hiroaki Nagano; Hiroshi Wada; Takehiro Noda; Hideo Ota; Bazarragchaa Damdinsuren; Shigeru Marubashi; Atsushi Miyamoto; Yutaka Takeda; Koji Umeshita; Keizo Dono; Morito Monden

Publisher: Springer Japan
Year: 2006
Tongue: English
Weight: 490 KB
Volume: 41
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-006-1907-x

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## Abstract ## BACKGROUND. To the authors' knowledge, there is no effective therapy for extrahepatic metastasis of hepatocellular carcinoma (HCC). In a pilot study, the results of combination therapy of S‐1, a novel oral dehydropyrimidine dehydrogenase (DPD) inhibitor, and interferon‐alpha (IFN‐α)