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A case of down syndrome with acute lymphoblastic leukemia and isochromosome Xp

✍ Scribed by Jillian M Baker; Max J Coppes; Birgitte Roland

Book ID: 114135671
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 114 KB
Volume: 147
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(03)00197-3

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## Abstract Previous cytogenetic studies of myeloid and acute lymphoblastic leukemias in children with Down syndrome (ML‐DS and DS‐ALL) have revealed significant differences in abnormality patterns between such cases and acute leukemias in general. Also, certain molecular genetic aberrations charac