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A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences

✍ Scribed by David Gisselsson; Mattias Höglund; Kevin P. O’Brien; Jan P. Dumanski; Fredrik Mertens; Nils Mandahl


Book ID
117469205
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
391 KB
Volume
133
Category
Article
ISSN
0304-3835

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COL1A1–PDGFB fusion in a ring chromosome
✍ Muriel Navarro; Marie-Pierre Simon; Colette Migeon; Claude Turc-Carel; Florence 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB

Dermatofibrosarcoma protuberans (DP), an infiltrative skin tumor of intermediate malignancy, presents specific cytogenetic features such as reciprocal translocations t(17;22)(q22;q13.1) or, more often, supernumerary ring chromosomes derived from t(17;22). Different translocations, including t(2;17)