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A case of Brooke–Spiegler syndrome with a new mutation in the CYLD gene

✍ Scribed by W. Heinritz; S. Grunewald; S. Strenge; A. Schütz; U.G. Froster; H.J. Glander; U. Paasch; J.C. Simon


Book ID
108668700
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
485 KB
Volume
154
Category
Article
ISSN
0007-0963

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Germline mutations in the cylindromatosis (CYLD) gene have been described in families with cylindromas, trichoepitheliomas, and/or spiradenomas. Brooke-Spiegler syndrome (BSS) is the autosomal dominant predisposition to skin appendageal neoplasms including cylindromas, trichoepitheliomas, and/or spi