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A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly

โœ Scribed by Schwake, Michael; Jentsch, Thomas J.; Friedrich, Thomas


Book ID
110033521
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
295 KB
Volume
4
Category
Article
ISSN
1469-221X

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Pleckstrin is an important intracellular protein involved in the phosphoinositide-signalling pathways of platelet activation. This protein contains both N- and C-terminal pleckstrin-homology (PH) domains (N-PH and C-PH). The crystal structure of C-PH was solved by molecular replacement and refined a