Adenylate cyclase of aggregation phase Dictyostelium discoideum is activated by extracellular adenosine 3', 5'-cyclic monophosphate (cAMP), and the cAMP synthesized is secreted. The distribution of the enzyme was determined in sucrose gradients loaded with whole cell lysates. Cell lysates prepared a
A cAMP-sensitive adenylate cyclase in Dictyostelium discoideum extracts
β Scribed by Claudette Klein; Michel Darmon
- Book ID
- 109310212
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 268 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0378-1097
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Haploid strains of Dictyostelium discoideum carrying radiation-sensitive mutations in both the radA and radC genes are more sensitive to UV light irradiation than the "additive" sensitivity of the single-mutant haploids. This synergistic interaction indicates that the radA and radC gene products are
We have previously presented evidence that cell-cell contact is the normal developmental signal to deactivate discoidin I gene expression in D discoideum [Berger EA, Clark JM: Proc Natl Acad Sci USA 80:4983, 19831. Here we provide genetic evidence to support this hypothesis by examining gene express