𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A calcium-dependent protein kinase is present in tetrahymena

✍ Scribed by Hargita Hegyesi; G. Csaba

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
492 KB
Volume
12
Category
Article
ISSN
0263-6484

No coin nor oath required. For personal study only.

✦ Synopsis

A Ca2+-dependent protein kinase of Tetrahymena thermophila has been partially purified and characterized. The molecular mass of the enzyme is less than that of similar enzymes (for example protein kinase C), being about 55 kDa. After purification and in the presence of Ca2+ the enzyme activity increased. The promoter of protein kinase C (PKC) activity, phorbol myristate acetate (PMA), increased the activity while the protein kinase inhibitor H-7 decreased the activity of the enzyme. The experiments demonstrate the presence, activity and similarity to vertebrate enzymes of a protein kinase at a low level of phylogeny.

πŸ“œ SIMILAR VOLUMES

Calcium/Calmodulin-dependent protein kin
Calcium/Calmodulin-dependent protein kinase activity in primary astrocyte cultures
✍ E. Babcock-Atkinson; Dr. M.D. Norenberg; L.O.B. Norenberg; J.T. Neary πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 725 KB

Calcium, calmodulin-dependent protein kinase (Ca/CaM kinase) is a n important component of calcium signalling mechanisms in the brain, but little is known about the properties of this protein phosphorylation system in astrocytes. Addition of calcium and calmodulin to supernatant or membrane fraction

In vivo glutamate neurotoxicity is assoc
In vivo glutamate neurotoxicity is associated with reductions in calcium/calmodulin-dependent protein kinase II immunoreactivity
✍ Alex M. Babcock; Hui Liu; Charles M. Paden; Severn B. Churn; Andrew J. Pittman πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 163 KB πŸ‘ 2 views

Calcium/calmodulin-dependent protein kinase II (CaM kinase) activity is inhibited in cultured hippocampal cells following direct application of glutamate. The goal of the present study was to determine if hippocampal regions that undergo delayed cell death following glutamate microinfusion would exh

Galantamine enhancement of long-term pot
Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation
✍ Shigeki Moriguchi; Norifumi Shioda; Feng Han; Jay Z. Yeh; Toshio Narahashi; Kohj πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 652 KB

## Abstract Galantamine, a novel Alzheimer's drug, is known to inhibit acetylcholinesterase activity and potentiate nicotinic acetylcholine receptor (nAChR) in the brain. We previously reported that galantamine potentiates the NMDA‐induced currents in primary cultured rat cortical neurons. We now s

Protein kinase A and calcium/calmodulin-
Protein kinase A and calcium/calmodulin-dependent protein kinase II regulate glycine and GABA release in auditory brain stem nuclei
✍ J. Zhang; S.K. Suneja; S.J. Potashner πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 351 KB

## Abstract We reported previously that unilateral cochlear ablation (UCA) in young adult guinea pigs induced protein kinase C (PKC)‐dependent plastic changes in the electrically evoked release of exogenous [^14^C]glycine ([^14^C]Gly) or [^14^C]‐γ‐aminobutyric acid ([^14^C]GABA) in several brain st

Protein kinase A and calcium/calmodulin-
Protein kinase A and calcium/calmodulin-dependent protein kinase II regulate D-[3H]aspartate release in auditory brain stem nuclei
✍ J. Zhang; S.K. Suneja; S.J. Potashner πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 193 KB

## Abstract We noted previously that after unilateral cochlear ablation (UCA) in young adult guinea pigs, plastic changes in glutamatergic transmitter release in several brain stem auditory nuclei depended on protein kinase C. In this study, we assessed whether such changes depended on protein kina