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A bridging study of xanomeline tartrate in Alzheimer's disease (AD)

✍ Scribed by N.R. Cutler; J.J. Sramek; R.D. Seifert; J.J. Conrad; T.S. Wardle; D.J. Hurley; L.M. Thoren

Book ID
118856854
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
163 KB
Volume
35
Category
Article
ISSN
0006-3223

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Xanomeline is a novel muscarinic receptor agonist relatively devoid of parasympathomimetic side effects. Xanomeline had high affinity for muscarinic receptors and much lower affinity for a variety of other neuronal receptors in radioligand binding assays. Functional studies in cell lines transfected