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A Block to mRNA Nuclear Export in S. cerevisiae Leads to Hyperadenylation of Transcripts that Accumulate at the Site of Transcription

✍ Scribed by Torben Heick Jensen; Kimberly Patricio; Terri McCarthy; Michael Rosbash


Book ID
117736516
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
979 KB
Volume
7
Category
Article
ISSN
1097-2765

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Chromosomal or allelic losses at 3p14 are common in a variety of human tumors, including those of the lung, breast, kidney, and head and neck. This suggests the existence of a tumor suppressor gene in this band. A promising candidate is the recently cloned FHIT gene, which spans the common fragile s